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How mitochondria produce reactive oxygen species

The production of ROS (reactive oxygen species) by mammalian mitochondria is important because it underlies oxidative damage in many pathologies and contributes to retrograde redox signalling from the organelle to the cytosol and nucleus. Superoxide (O(2)(•−)) is the proximal mitochondrial ROS, and...

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Detalles Bibliográficos
Autor principal: Murphy, Michael P.
Formato: Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605959/
https://www.ncbi.nlm.nih.gov/pubmed/19061483
http://dx.doi.org/10.1042/BJ20081386