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How mitochondria produce reactive oxygen species
The production of ROS (reactive oxygen species) by mammalian mitochondria is important because it underlies oxidative damage in many pathologies and contributes to retrograde redox signalling from the organelle to the cytosol and nucleus. Superoxide (O(2)(•−)) is the proximal mitochondrial ROS, and...
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Formato: | Texto |
Lenguaje: | English |
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Portland Press Ltd.
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605959/ https://www.ncbi.nlm.nih.gov/pubmed/19061483 http://dx.doi.org/10.1042/BJ20081386 |