Eag1 Expression Interferes with Hypoxia Homeostasis and Induces Angiogenesis in Tumors

Ether-á-go-go-1 (Eag1) is a CNS-localized voltage-gated potassium channel that is found ectopically expressed in a majority of extracranial solid tumors. While circumstantial evidence linking Eag1 to tumor biology has been well established, the mechanisms by which the channel contributes to tumor pr...

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Detalles Bibliográficos
Autores principales: Downie, Bryan R., Sánchez, Araceli, Knötgen, Hendrik, Contreras-Jurado, Constanza, Gymnopoulos, Marco, Weber, Claudia, Stühmer, Walter, Pardo, Luis A.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2008
Materias:
Mechanisms of Signal Transduction
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2606018/
https://www.ncbi.nlm.nih.gov/pubmed/18927085
http://dx.doi.org/10.1074/jbc.M801830200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2606018/
https://www.ncbi.nlm.nih.gov/pubmed/18927085
http://dx.doi.org/10.1074/jbc.M801830200

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