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Eag1 Expression Interferes with Hypoxia Homeostasis and Induces Angiogenesis in Tumors

Ether-á-go-go-1 (Eag1) is a CNS-localized voltage-gated potassium channel that is found ectopically expressed in a majority of extracranial solid tumors. While circumstantial evidence linking Eag1 to tumor biology has been well established, the mechanisms by which the channel contributes to tumor pr...

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Detalles Bibliográficos
Autores principales:	Downie, Bryan R., Sánchez, Araceli, Knötgen, Hendrik, Contreras-Jurado, Constanza, Gymnopoulos, Marco, Weber, Claudia, Stühmer, Walter, Pardo, Luis A.
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2008
Materias:	Mechanisms of Signal Transduction
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2606018/ https://www.ncbi.nlm.nih.gov/pubmed/18927085 http://dx.doi.org/10.1074/jbc.M801830200

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