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Aging Impairs Recipient T Cell Intrinsic and Extrinsic Factors in Response to Transplantation

BACKGROUND: As increasing numbers of older people are listed for solid organ transplantation, there is an urgent need to better understand how aging modifies alloimmune responses. Here, we investigated whether aging impairs the ability of donor dendritic cells or recipient immunity to prime alloimmu...

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Detalles Bibliográficos
Autores principales: Shen, Hua, Tesar, Bethany M., Du, Wei, Goldstein, Daniel R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2606020/
https://www.ncbi.nlm.nih.gov/pubmed/19119314
http://dx.doi.org/10.1371/journal.pone.0004097