Human Polycomb 2 Protein Is a SUMO E3 Ligase and Alleviates Substrate-Induced Inhibition of Cystathionine β-Synthase Sumoylation

Human cystathionine β-synthase (CBS) catalyzes the first irreversible step in the transsulfuration pathway and commits homocysteine to the synthesis of cysteine. Mutations in CBS are the most common cause of severe hereditary hyperhomocysteinemia. A yeast two-hybrid approach to screen for proteins t...

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Detalles Bibliográficos
Autores principales: Agrawal, Nitish, Banerjee, Ruma
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2606060/
https://www.ncbi.nlm.nih.gov/pubmed/19107218
http://dx.doi.org/10.1371/journal.pone.0004032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2606060/
https://www.ncbi.nlm.nih.gov/pubmed/19107218
http://dx.doi.org/10.1371/journal.pone.0004032

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