Recombinant amyloid beta-peptide production by coexpression with an affibody ligand

BACKGROUND: Oligomeric and fibrillar aggregates of the amyloid β-peptide (Aβ) have been implicated in the pathogenesis of Alzheimer's disease (AD). The characterization of Aβ assemblies is essential for the elucidation of the mechanisms of Aβ neurotoxicity, but requires large quantities of pure...

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Detalles Bibliográficos
Autores principales: Macao, Bertil, Hoyer, Wolfgang, Sandberg, Anders, Brorsson, Ann-Christin, Dobson, Christopher M, Härd, Torleif
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2606684/
https://www.ncbi.nlm.nih.gov/pubmed/18973685
http://dx.doi.org/10.1186/1472-6750-8-82

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2606684/
https://www.ncbi.nlm.nih.gov/pubmed/18973685
http://dx.doi.org/10.1186/1472-6750-8-82

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