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High-fidelity correction of genomic uracil by human mismatch repair activities
BACKGROUND: Deamination of cytosine to produce uracil is a common and potentially mutagenic lesion in genomic DNA. U•G mismatches occur spontaneously throughout the genome, where they are repaired by factors associated with the base excision repair pathway. U•G mismatches are also the initiating les...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2606688/ https://www.ncbi.nlm.nih.gov/pubmed/18954457 http://dx.doi.org/10.1186/1471-2199-9-94 |