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Dipeptidyl Peptidase-4 Inhibition by Vildagliptin and the Effect on Insulin Secretion and Action in Response to Meal Ingestion in Type 2 Diabetes

OBJECTIVE—The purpose of this study was to determine the mechanism by which dipeptidyl peptidase-4 inhibitors lower postprandial glucose concentrations. RESEARCH DESIGN AND METHODS—We measured insulin secretion and action as well as glucose effectiveness in 14 subjects with type 2 diabetes who recei...

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Detalles Bibliográficos
Autores principales: Dalla Man, Chiara, Bock, Gerlies, Giesler, Paula D., Serra, Denise B., Ligueros Saylan, Monica, Foley, James E., Camilleri, Michael, Toffolo, Gianna, Cobelli, Claudio, Rizza, Robert A., Vella, Adrian
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2606822/
https://www.ncbi.nlm.nih.gov/pubmed/18931099
http://dx.doi.org/10.2337/dc08-1512