Allopurinol and Nitric Oxide Activity in the Cerebral Circulation of Those With Diabetes: A randomized trial

OBJECTIVE—Type 2 diabetes increases risk of stroke, perhaps because of impaired cerebrovascular basal nitric oxide (NO) activity. We investigated whether this activity is improved by a 2-week course of the xanthine oxidase inhibitor allopurinol. RESEARCH DESIGN AND METHODS—We performed a randomized,...

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Detalles Bibliográficos
Autores principales: Dawson, Jesse, Quinn, Terry, Harrow, Craig, Lees, Kennedy R., Weir, Christopher J., Cleland, Stephen J., Walters, Matthew R.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Pathophysiology/Complications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2606848/
https://www.ncbi.nlm.nih.gov/pubmed/18945924
http://dx.doi.org/10.2337/dc08-1179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2606848/
https://www.ncbi.nlm.nih.gov/pubmed/18945924
http://dx.doi.org/10.2337/dc08-1179

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