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Allopurinol and Nitric Oxide Activity in the Cerebral Circulation of Those With Diabetes: A randomized trial

OBJECTIVE—Type 2 diabetes increases risk of stroke, perhaps because of impaired cerebrovascular basal nitric oxide (NO) activity. We investigated whether this activity is improved by a 2-week course of the xanthine oxidase inhibitor allopurinol. RESEARCH DESIGN AND METHODS—We performed a randomized,...

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Detalles Bibliográficos
Autores principales:	Dawson, Jesse, Quinn, Terry, Harrow, Craig, Lees, Kennedy R., Weir, Christopher J., Cleland, Stephen J., Walters, Matthew R.
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2009
Materias:	Pathophysiology/Complications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2606848/ https://www.ncbi.nlm.nih.gov/pubmed/18945924 http://dx.doi.org/10.2337/dc08-1179

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