All-trans Retinoic Acid Inhibits Type 1 Diabetes by T Regulatory (Treg)-Dependent Suppression of Interferon-γ–Producing T-cells Without Affecting Th17 Cells

OBJECTIVE—All-trans retinoic acid (ATRA), a potent derivative of vitamin A, can regulate immune responses. However, its role in inducing immune tolerance associated with the prevention of islet inflammation and inhibition of type 1 diabetes remains unclear. RESEARCH DESIGN AND METHODS—We investigate...

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Detalles Bibliográficos
Autores principales: Van, Yang-Hau, Lee, Wen-Hui, Ortiz, Serina, Lee, Mi-Heon, Qin, Han-Jun, Liu, Chih-Pin
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Immunology and Transplantation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2606864/
https://www.ncbi.nlm.nih.gov/pubmed/18984738
http://dx.doi.org/10.2337/db08-1154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2606864/
https://www.ncbi.nlm.nih.gov/pubmed/18984738
http://dx.doi.org/10.2337/db08-1154

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