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Hypoxia Decreases Insulin Signaling Pathways in Adipocytes

OBJECTIVE—Obesity is characterized by an overgrowth of adipose tissue that leads to the formation of hypoxic areas within this tissue. We investigated whether this phenomenon could be responsible for insulin resistance by studying the effect of hypoxia on the insulin signaling pathway in adipocytes....

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Detalles Bibliográficos
Autores principales: Regazzetti, Claire, Peraldi, Pascal, Grémeaux, Thierry, Najem-Lendom, Rosanna, Ben-Sahra, Issam, Cormont, Mireille, Bost, Frédéric, Le Marchand-Brustel, Yannick, Tanti, Jean-François, Giorgetti-Peraldi, Sophie
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2606898/
https://www.ncbi.nlm.nih.gov/pubmed/18984735
http://dx.doi.org/10.2337/db08-0457