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Hypoxia Decreases Insulin Signaling Pathways in Adipocytes
OBJECTIVE—Obesity is characterized by an overgrowth of adipose tissue that leads to the formation of hypoxic areas within this tissue. We investigated whether this phenomenon could be responsible for insulin resistance by studying the effect of hypoxia on the insulin signaling pathway in adipocytes....
Autores principales: | Regazzetti, Claire, Peraldi, Pascal, Grémeaux, Thierry, Najem-Lendom, Rosanna, Ben-Sahra, Issam, Cormont, Mireille, Bost, Frédéric, Le Marchand-Brustel, Yannick, Tanti, Jean-François, Giorgetti-Peraldi, Sophie |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2606898/ https://www.ncbi.nlm.nih.gov/pubmed/18984735 http://dx.doi.org/10.2337/db08-0457 |
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