Molecular Basis for Cation Selectivity in Claudin-2–based Paracellular Pores: Identification of an Electrostatic Interaction Site

Paracellular ion transport in epithelia is mediated by pores formed by members of the claudin family. The degree of selectivity and the molecular mechanism of ion permeation through claudin pores are poorly understood. By expressing a high-conductance claudin isoform, claudin-2, in high-resistance M...

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Detalles Bibliográficos
Autores principales: Yu, Alan S.L., Cheng, Mary H., Angelow, Susanne, Günzel, Dorothee, Kanzawa, Sanae A., Schneeberger, Eveline E., Fromm, Michael, Coalson, Rob D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2606938/
https://www.ncbi.nlm.nih.gov/pubmed/19114638
http://dx.doi.org/10.1085/jgp.200810154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2606938/
https://www.ncbi.nlm.nih.gov/pubmed/19114638
http://dx.doi.org/10.1085/jgp.200810154

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