PARP-1 ensures regulation of replication fork progression by homologous recombination on damaged DNA

Poly-ADP ribose polymerase 1 (PARP-1) is activated by DNA damage and has been implicated in the repair of single-strand breaks (SSBs). Involvement of PARP-1 in other DNA damage responses remains controversial. In this study, we show that PARP-1 is required for replication fork slowing on damaged DNA...

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Detalles Bibliográficos
Autores principales: Sugimura, Kazuto, Takebayashi, Shin-ichiro, Taguchi, Hiroshi, Takeda, Shunichi, Okumura, Katsuzumi
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2606964/
https://www.ncbi.nlm.nih.gov/pubmed/19103807
http://dx.doi.org/10.1083/jcb.200806068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2606964/
https://www.ncbi.nlm.nih.gov/pubmed/19103807
http://dx.doi.org/10.1083/jcb.200806068

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