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PARP-1 ensures regulation of replication fork progression by homologous recombination on damaged DNA

Poly-ADP ribose polymerase 1 (PARP-1) is activated by DNA damage and has been implicated in the repair of single-strand breaks (SSBs). Involvement of PARP-1 in other DNA damage responses remains controversial. In this study, we show that PARP-1 is required for replication fork slowing on damaged DNA...

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Detalles Bibliográficos
Autores principales:	Sugimura, Kazuto, Takebayashi, Shin-ichiro, Taguchi, Hiroshi, Takeda, Shunichi, Okumura, Katsuzumi
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2008
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2606964/ https://www.ncbi.nlm.nih.gov/pubmed/19103807 http://dx.doi.org/10.1083/jcb.200806068

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