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Localized Populations of CD8(low/−) MHC Class I Tetramer(+) SIV-Specific T Cells in Lymphoid Follicles and Genital Epithelium

CD8 T cells play an important role in controlling viral infections. We investigated the in situ localization of simian immunodeficiency virus (SIV)-specific T cells in lymph and genital tissues from SIV-infected macaques using MHC-class I tetramers. The majority of tetramer-binding cells localized i...

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Detalles Bibliográficos
Autores principales: Hong, Jung Joo, Reynolds, Matthew R., Mattila, Teresa L., Hage, Aaron, Watkins, David I., Miller, Christopher J., Skinner, Pamela J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2607009/
https://www.ncbi.nlm.nih.gov/pubmed/19122815
http://dx.doi.org/10.1371/journal.pone.0004131