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RIG-I and dsRNA-Induced IFNβ Activation

Except for viruses that initiate RNA synthesis with a protein primer (e.g., picornaviruses), most RNA viruses initiate RNA synthesis with an NTP, and at least some of their viral (ppp)RNAs remain unblocked during the infection. Consistent with this, most viruses require RIG-I to mount an innate immu...

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Detalles Bibliográficos
Autores principales: Hausmann, Stéphane, Marq, Jean-Baptiste, Tapparel, Caroline, Kolakofsky, Daniel, Garcin, Dominique
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2607022/
https://www.ncbi.nlm.nih.gov/pubmed/19115016
http://dx.doi.org/10.1371/journal.pone.0003965