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Two Host Factors Regulate Persistence of H7(a)-Specific T Cells Injected in Tumor-Bearing Mice

BACKGROUND: Injection of CD8 T cells primed against immunodominant minor histocompatibility antigens (MiHA) such as H7(a) can eradicate leukemia and solid tumors. To understand why MiHA-targeted T cells have such a potent antitumor effect it is essential to evaluate their in vivo behavior. In the pr...

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Detalles Bibliográficos
Autores principales: Meunier, Marie-Christine, Baron, Chantal, Perreault, Claude
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2607026/
https://www.ncbi.nlm.nih.gov/pubmed/19127288
http://dx.doi.org/10.1371/journal.pone.0004116