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Strong Eukaryotic IRESs Have Weak Secondary Structure

BACKGROUND: The objective of this work was to investigate the hypothesis that eukaryotic Internal Ribosome Entry Sites (IRES) lack secondary structure and to examine the generality of the hypothesis. METHODOLOGY/PRINCIPAL FINDINGS: IRESs of the yeast and the fruit fly are located in the 5′UTR immedi...

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Detalles Bibliográficos
Autores principales: Xia, Xuhua, Holcik, Martin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2607549/
https://www.ncbi.nlm.nih.gov/pubmed/19125192
http://dx.doi.org/10.1371/journal.pone.0004136