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IL2RA/CD25 Gene Polymorphisms: Uneven Association with Multiple Sclerosis (MS) and Type 1 Diabetes (T1D)

BACKGROUND: IL-2 receptor (IL2R) alpha is the specific component of the high affinity IL2R system involved in the immune response and in the control of autoimmunity. METHODS AND RESULTS: Here we perform a replication and fine mapping of the IL2RA gene region analyzing 3 SNPs previously associated wi...

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Detalles Bibliográficos
Autores principales: Alcina, Antonio, Fedetz, María, Ndagire, Dorothy, Fernández, Oscar, Leyva, Laura, Guerrero, Miguel, Abad-Grau, María M., Arnal, Carmen, Delgado, Concepción, Lucas, Miguel, Izquierdo, Guillermo, Matesanz, Fuencisla
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2607550/
https://www.ncbi.nlm.nih.gov/pubmed/19125193
http://dx.doi.org/10.1371/journal.pone.0004137