Cargando…

Calnexin is not essential for mammalian rod opsin biogenesis

PURPOSE: Misfolding mutations in rod opsin are a major cause of the inherited blindness retinitis pigmentosa. Therefore, understanding the role of molecular chaperones in facilitating rod opsin biogenesis and the response to mutant rod opsin is important for retinal disease and fundamental retinal c...

Descripción completa

Detalles Bibliográficos
Autores principales: Kosmaoglou, Maria, Cheetham, Michael E.
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2610292/
https://www.ncbi.nlm.nih.gov/pubmed/19116670