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Functional characterization of cohesin subunit SCC1 in Trypanosoma brucei and dissection of mutant phenotypes in two life cycle stages

In yeast and metazoa, structural maintenance of chromosome (SMC) complexes play key roles in chromosome segregation, architecture and DNA repair. The main function of the cohesin complex is to hold replicated sister chromatids together until segregation at anaphase, which is dependent on proteolytic...

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Detalles Bibliográficos
Autores principales: Gluenz, Eva, Sharma, Reuben, Carrington, Mark, Gull, Keith
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2610385/
https://www.ncbi.nlm.nih.gov/pubmed/18554326
http://dx.doi.org/10.1111/j.1365-2958.2008.06320.x