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Additive Antinociception between Intrathecal Sildenafil and Morphine in the Rat Formalin Test

The possible characteristics of spinal interaction between sildenafil (phosphodiesterase 5 inhibitor) and morphine on formalin-induced nociception in rats was examined. Then the role of the opioid receptor in the effect of sildenafil was further investigated. Catheters were inserted into the intrath...

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Detalles Bibliográficos
Autores principales: Yoon, Myung Ha, Park, Kyung Deok, Lee, Hyung Gon, Kim, Woong Mo, An, Tae Hoon, Kim, Yeo Ok, Huang, Lan Ji, Hua, Cui Jin
Formato: Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2610640/
https://www.ncbi.nlm.nih.gov/pubmed/19119449
http://dx.doi.org/10.3346/jkms.2008.23.6.1033