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Additive Antinociception between Intrathecal Sildenafil and Morphine in the Rat Formalin Test
The possible characteristics of spinal interaction between sildenafil (phosphodiesterase 5 inhibitor) and morphine on formalin-induced nociception in rats was examined. Then the role of the opioid receptor in the effect of sildenafil was further investigated. Catheters were inserted into the intrath...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Korean Academy of Medical Sciences
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2610640/ https://www.ncbi.nlm.nih.gov/pubmed/19119449 http://dx.doi.org/10.3346/jkms.2008.23.6.1033 |