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Interpreting missense mutations in Human TRIM5alpha by computational methods
BACKGROUND: The human restriction factor TRIM5α may play an important role in regulation of the human immunodeficiency virus (HIV). It is unclear whether non-synonymous single nucleotide polymorphisms (nsSNP) in TRIM5α affect the clinical course of HIV infection. FINDINGS: We surveyed the literature...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2611994/ https://www.ncbi.nlm.nih.gov/pubmed/19025647 http://dx.doi.org/10.1186/1756-0500-1-116 |