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The content of African diets is adequate to achieve optimal efficacy with fixed-dose artemether-lumefantrine: a review of the evidence

A fixed-dose combination of artemether-lumefantrine (AL, Coartem(®)) has shown high efficacy, good tolerability and cost-effectiveness in adults and children with uncomplicated malaria caused by Plasmodium falciparum. Lumefantrine bioavailability is enhanced by food, particularly fat. As the fat con...

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Detalles Bibliográficos
Autores principales: Premji, Zulfiqarali G, Abdulla, Salim, Ogutu, Bernhards, Ndong, Alice, Falade, Catherine O, Sagara, Issaka, Mulure, Nathan, Nwaiwu, Obiyo, Kokwaro, Gilbert
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2611997/
https://www.ncbi.nlm.nih.gov/pubmed/19032767
http://dx.doi.org/10.1186/1475-2875-7-244