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The content of African diets is adequate to achieve optimal efficacy with fixed-dose artemether-lumefantrine: a review of the evidence
A fixed-dose combination of artemether-lumefantrine (AL, Coartem(®)) has shown high efficacy, good tolerability and cost-effectiveness in adults and children with uncomplicated malaria caused by Plasmodium falciparum. Lumefantrine bioavailability is enhanced by food, particularly fat. As the fat con...
Autores principales: | Premji, Zulfiqarali G, Abdulla, Salim, Ogutu, Bernhards, Ndong, Alice, Falade, Catherine O, Sagara, Issaka, Mulure, Nathan, Nwaiwu, Obiyo, Kokwaro, Gilbert |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2611997/ https://www.ncbi.nlm.nih.gov/pubmed/19032767 http://dx.doi.org/10.1186/1475-2875-7-244 |
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