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Frequently increased epidermal growth factor receptor (EGFR) copy numbers and decreased BRCA1 mRNA expression in Japanese triple-negative breast cancers

BACKGROUND: Triple-negative breast cancer (estrogen receptor-, progesterone receptor-, and HER2-negative) (TNBC) is a high risk breast cancer that lacks specific therapy targeting these proteins. METHODS: We studied 969 consecutive Japanese patients diagnosed with invasive breast cancer from January...

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Detalles Bibliográficos
Autores principales: Toyama, Tatsuya, Yamashita, Hiroko, Kondo, Naoto, Okuda, Katsuhiro, Takahashi, Satoru, Sasaki, Hidefumi, Sugiura, Hiroshi, Iwase, Hirotaka, Fujii, Yoshitaka
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2612006/
https://www.ncbi.nlm.nih.gov/pubmed/18950515
http://dx.doi.org/10.1186/1471-2407-8-309