mtDNA depletion confers specific gene expression profiles in human cells grown in culture and in xenograft

BACKGROUND: Interactions between the gene products encoded by the mitochondrial and nuclear genomes play critical roles in eukaryotic cellular function. However, the effects mitochondrial DNA (mtDNA) levels have on the nuclear transcriptome have not been defined under physiological conditions. In or...

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Detalles Bibliográficos
Autores principales: Magda, Darren, Lecane, Philip, Prescott, Julia, Thiemann, Patricia, Ma, Xuan, Dranchak, Patricia K, Toleno, Donna M, Ramaswamy, Krishna, Siegmund, Kimberly D, Hacia, Joseph G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2612029/
https://www.ncbi.nlm.nih.gov/pubmed/18980691
http://dx.doi.org/10.1186/1471-2164-9-521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2612029/
https://www.ncbi.nlm.nih.gov/pubmed/18980691
http://dx.doi.org/10.1186/1471-2164-9-521

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