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Refined annotation and assembly of the Tetrahymena thermophila genome sequence through EST analysis, comparative genomic hybridization, and targeted gap closure

BACKGROUND: Tetrahymena thermophila, a widely studied model for cellular and molecular biology, is a binucleated single-celled organism with a germline micronucleus (MIC) and somatic macronucleus (MAC). The recent draft MAC genome assembly revealed low sequence repetitiveness, a result of the epigen...

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Detalles Bibliográficos
Autores principales: Coyne, Robert S, Thiagarajan, Mathangi, Jones, Kristie M, Wortman, Jennifer R, Tallon, Luke J, Haas, Brian J, Cassidy-Hanley, Donna M, Wiley, Emily A, Smith, Joshua J, Collins, Kathleen, Lee, Suzanne R, Couvillion, Mary T, Liu, Yifan, Garg, Jyoti, Pearlman, Ronald E, Hamilton, Eileen P, Orias, Eduardo, Eisen, Jonathan A, Methé, Barbara A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2612030/
https://www.ncbi.nlm.nih.gov/pubmed/19036158
http://dx.doi.org/10.1186/1471-2164-9-562