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Differential replication dynamics for large and small Vibrio chromosomes affect gene dosage, expression and location

BACKGROUND: Replication of bacterial chromosomes increases copy numbers of genes located near origins of replication relative to genes located near termini. Such differential gene dosage depends on replication rate, doubling time and chromosome size. Although little explored, differential gene dosag...

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Detalles Bibliográficos
Autores principales: Dryselius, Rikard, Izutsu, Kaori, Honda, Takeshi, Iida, Tetsuya
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2612033/
https://www.ncbi.nlm.nih.gov/pubmed/19032792
http://dx.doi.org/10.1186/1471-2164-9-559