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Cell adhesion to agrin presented as a nanopatterned substrate is consistent with an interaction with the extracellular matrix and not transmembrane adhesion molecules

BACKGROUND: Molecular spacing is important for cell adhesion in a number of ways, ranging from the ordered arrangement of matrix polymers extracellularly, to steric hindrance of adhesion/signaling complexes intracellularly. This has been demonstrated using nanopatterned RGD peptides, a canonical ext...

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Detalles Bibliográficos
Autores principales: Wolfram, Tobias, Spatz, Joachim P, Burgess, Robert W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2612657/
https://www.ncbi.nlm.nih.gov/pubmed/19055842
http://dx.doi.org/10.1186/1471-2121-9-64