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Ovarian cancer plasticity and epigenomics in the acquisition of a stem-like phenotype

Aggressive epithelial ovarian cancer (EOC) is genetically and epigenetically distinct from normal ovarian surface epithelial cells (OSE) and early neoplasia. Co-expression of epithelial and mesenchymal markers in EOC suggests an involvement of epithelial-mesenchymal transition (EMT) in cancer initia...

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Detalles Bibliográficos
Autores principales: Berry, Nicholas B, Bapat, Sharmila A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2612659/
https://www.ncbi.nlm.nih.gov/pubmed/19025622
http://dx.doi.org/10.1186/1757-2215-1-8