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Probing of Actinobacillus pleuropneumoniae ApxIIIA toxin-dependent cytotoxicity towards mammalian peripheral blood mononucleated cells

BACKGROUND: Actinobacillus pleuropneumoniae, the causative bacterial agent of porcine pleuropneumonia, produces Apx toxins which belong to RTX toxin family and are recognized as the major virulence factors. So far, their target receptor(s) has not been identified and the disease cytopathogenesis rem...

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Detalles Bibliográficos
Autores principales: Vanden Bergh, Philippe GAC, Zecchinon, Laurent LM, Fett, Thomas, Desmecht, Daniel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2612674/
https://www.ncbi.nlm.nih.gov/pubmed/19046441
http://dx.doi.org/10.1186/1756-0500-1-121