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The use of gamma-irradiation and ultraviolet-irradiation in the preparation of human melanoma cells for use in autologous whole-cell vaccines

BACKGROUND: Human cancer vaccines incorporating autologous tumor cells carry a risk of implantation and subsequent metastasis of viable tumor cells into the patient who is being treated. Despite the fact that the melanoma cell preparations used in a recent vaccine trial (Mel37) were gamma-irradiated...

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Detalles Bibliográficos
Autores principales: Deacon, Donna H, Hogan, Kevin T, Swanson, Erin M, Chianese-Bullock, Kimberly A, Denlinger, Chadrick E, Czarkowski, Andrea R, Schrecengost, Randy S, Patterson, James W, Teague, Mark W, Slingluff, Craig L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2612687/
https://www.ncbi.nlm.nih.gov/pubmed/19055839
http://dx.doi.org/10.1186/1471-2407-8-360