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Cationic nano-copolymers mediated IKKβ targeting siRNA inhibit the proliferation of human Tenon’s capsule fibroblasts in vitro

PURPOSE: To synthesize a ternary cationic copolymer called CS-g-(PEI-b-mPEG) and characterize its features as a non-viral siRNA carrier; in turn, to investigate the influence of small interfering RNA (siRNA) targeting IκB kinase subunit β (IKKβ) on the proliferation of human Tenon’s capsule fibrobla...

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Detalles Bibliográficos
Autores principales: Duan, Yongheng, Guan, Xipeng, Ge, Jian, Quan, Daping, Zhuo, Yehong, Ye, Hehua, Shao, Tingting
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613073/
https://www.ncbi.nlm.nih.gov/pubmed/19137061