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Alternate serotype adenovector provides long-term therapeutic gene expression in the eye

PURPOSE: To determine whether the duration of transgene expression from an alternate adenovector serotype, Ad35, can provide advantages over an Ad5 serotype vector following a single intravitreal (IVT) administration. METHODS: To assess the transgene expression profile, mice received one IVT injecti...

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Detalles Bibliográficos
Autores principales: Hamilton, Melissa M., Byrnes, Gordon A., Gall, Jason G., Brough, Douglas E., King, C. Richter, Wei, Lisa L.
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613074/
https://www.ncbi.nlm.nih.gov/pubmed/19122827