Glutamate receptor activation triggers OPA1 release and induces apoptotic cell death in ischemic rat retina

PURPOSE: Glutamate receptor activation-induced excitotoxicity has been hypothesized to cause retinal ganglion cell (RGC) death in glaucoma and to link mitochondrial dysfunction in both acute and chronic neurodegenerative disorders. However, the relationships among elevated intraocular pressure (IOP)...

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Detalles Bibliográficos
Autores principales: Ju, Won-Kyu, Lindsey, James D., Angert, Mila, Patel, Ankur, Weinreb, Robert N.
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613079/
https://www.ncbi.nlm.nih.gov/pubmed/19122832

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613079/
https://www.ncbi.nlm.nih.gov/pubmed/19122832

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