Analysis of EGFR, HER2, and TOP2A gene status and chromosomal polysomy in gastric adenocarcinoma from Chinese patients

BACKGROUND: The EGFR and HER2 genes are located on chromosomes 7 and 17, respectively. They are therapeutic targets in some tumors. The TOP2A gene, which is located near HER2 on chromosome 17, is the target of many chemotherapeutic agents, and co-amplification of HER2 and TOP2A has been described in...

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Detalles Bibliográficos
Autores principales: Liang, Zhiyong, Zeng, Xuan, Gao, Jie, Wu, Shafei, Wang, Peng, Shi, Xiaohua, Zhang, Jing, Liu, Tonghua
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613415/
https://www.ncbi.nlm.nih.gov/pubmed/19061514
http://dx.doi.org/10.1186/1471-2407-8-363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613415/
https://www.ncbi.nlm.nih.gov/pubmed/19061514
http://dx.doi.org/10.1186/1471-2407-8-363

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