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Analysis of EGFR, HER2, and TOP2A gene status and chromosomal polysomy in gastric adenocarcinoma from Chinese patients

BACKGROUND: The EGFR and HER2 genes are located on chromosomes 7 and 17, respectively. They are therapeutic targets in some tumors. The TOP2A gene, which is located near HER2 on chromosome 17, is the target of many chemotherapeutic agents, and co-amplification of HER2 and TOP2A has been described in...

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Detalles Bibliográficos
Autores principales:	Liang, Zhiyong, Zeng, Xuan, Gao, Jie, Wu, Shafei, Wang, Peng, Shi, Xiaohua, Zhang, Jing, Liu, Tonghua
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613415/ https://www.ncbi.nlm.nih.gov/pubmed/19061514 http://dx.doi.org/10.1186/1471-2407-8-363

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