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8-Oxo-7,8-dihydro-2'-deoxyguanosine Forms a Relatively Unstable Tetrameric Structure Compared with 2'-Deoxyguanosine

The hydrogen-bonded guanine tetrad, or G-quartet has been implicated in a variety of biological roles, including the function of chromosome telomeres. Here effect of the hydroxylation of guanosine at the 8 position on the G-quartet formation was examined. Electrospray inonization mass (ESI-MS) spect...

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Detalles Bibliográficos
Autor principal: Iwahashi, Hideo
Formato: Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613500/
https://www.ncbi.nlm.nih.gov/pubmed/19177189
http://dx.doi.org/10.3164/jcbn.08-157