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The Characterization of High-Fat Diet and Multiple Low-Dose Streptozotocin Induced Type 2 Diabetes Rat Model

Aim. Based on the previously established method, we developed a better and stable animal model of type 2 diabetes mellitus by high-fat diet combined with multiple low-dose STZ injections. Meanwhile, this new model was used to evaluate the antidiabetic effect of berberine. Method. Wistar male rats fe...

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Detalles Bibliográficos
Autores principales: Zhang, Ming, Lv, Xiao-Yan, Li, Jing, Xu, Zhi-Gang, Chen, Li
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613511/
https://www.ncbi.nlm.nih.gov/pubmed/19132099
http://dx.doi.org/10.1155/2008/704045