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Joint Evolutionary Trees: A Large-Scale Method To Predict Protein Interfaces Based on Sequence Sampling

The Joint Evolutionary Trees (JET) method detects protein interfaces, the core residues involved in the folding process, and residues susceptible to site-directed mutagenesis and relevant to molecular recognition. The approach, based on the Evolutionary Trace (ET) method, introduces a novel way to t...

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Detalles Bibliográficos
Autores principales: Engelen, Stefan, Trojan, Ladislas A., Sacquin-Mora, Sophie, Lavery, Richard, Carbone, Alessandra
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613531/
https://www.ncbi.nlm.nih.gov/pubmed/19165315
http://dx.doi.org/10.1371/journal.pcbi.1000267