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Genomic Analysis Reveals a Potential Role for Cell Cycle Perturbation in HCV-Mediated Apoptosis of Cultured Hepatocytes

The mechanisms of liver injury associated with chronic HCV infection, as well as the individual roles of both viral and host factors, are not clearly defined. However, it is becoming increasingly clear that direct cytopathic effects, in addition to immune-mediated processes, play an important role i...

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Detalles Bibliográficos
Autores principales: Walters, Kathie-Anne, Syder, Andrew J., Lederer, Sharon L., Diamond, Deborah L., Paeper, Bryan, Rice, Charles M., Katze, Michael G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613535/
https://www.ncbi.nlm.nih.gov/pubmed/19148281
http://dx.doi.org/10.1371/journal.ppat.1000269