A Factor Graph Nested Effects Model To Identify Networks from Genetic Perturbations

Complex phenotypes such as the transformation of a normal population of cells into cancerous tissue result from a series of molecular triggers gone awry. We describe a method that searches for a genetic network consistent with expression changes observed under the knock-down of a set of genes that s...

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Detalles Bibliográficos
Autores principales: Vaske, Charles J., House, Carrie, Luu, Truong, Frank, Bryan, Yeang, Chen-Hsiang, Lee, Norman H., Stuart, Joshua M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613752/
https://www.ncbi.nlm.nih.gov/pubmed/19180177
http://dx.doi.org/10.1371/journal.pcbi.1000274

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613752/
https://www.ncbi.nlm.nih.gov/pubmed/19180177
http://dx.doi.org/10.1371/journal.pcbi.1000274

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