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A Factor Graph Nested Effects Model To Identify Networks from Genetic Perturbations
Complex phenotypes such as the transformation of a normal population of cells into cancerous tissue result from a series of molecular triggers gone awry. We describe a method that searches for a genetic network consistent with expression changes observed under the knock-down of a set of genes that s...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613752/ https://www.ncbi.nlm.nih.gov/pubmed/19180177 http://dx.doi.org/10.1371/journal.pcbi.1000274 |