Nutritional status and serum zinc and selenium levels in Iranian HIV infected individuals

BACKGROUND: Human immunodeficiency virus infected individuals are prone to malnutrition due to increased energy requirements, enteropathy and increased catabolism. Trace elements such as zinc and selenium have major role in maintaining a healthy immune system. This study was designed to evaluate the...

Descripción completa

Detalles Bibliográficos
Autores principales: Khalili, H, Soudbakhsh, A, Hajiabdolbaghi, M, Dashti-Khavidaki, S, Poorzare, A, Saeedi, AA, Sharififar, R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613901/
https://www.ncbi.nlm.nih.gov/pubmed/19068104
http://dx.doi.org/10.1186/1471-2334-8-165
_version_ 1782163208348368896
author Khalili, H
Soudbakhsh, A
Hajiabdolbaghi, M
Dashti-Khavidaki, S
Poorzare, A
Saeedi, AA
Sharififar, R
author_facet Khalili, H
Soudbakhsh, A
Hajiabdolbaghi, M
Dashti-Khavidaki, S
Poorzare, A
Saeedi, AA
Sharififar, R
author_sort Khalili, H
collection PubMed
description BACKGROUND: Human immunodeficiency virus infected individuals are prone to malnutrition due to increased energy requirements, enteropathy and increased catabolism. Trace elements such as zinc and selenium have major role in maintaining a healthy immune system. This study was designed to evaluate the nutritional status of Iranian subjects who were newly diagnosed with human immunodeficiency virus infection and to compare serum level of zinc and selenium in these patients with those of the sex and aged match healthy subjects. METHODS: After an interview and physical examination, nutritional assessment was done based on clinical and anthropometric parameters. Body mass index (normal range 18.5–27 kg/m(2 )based on age) of less than 16, 16–16.9 and 17–18.4 kg/m(2 )were considered as severe, moderate and mild malnutrition respectively. Serum level of zinc and selenium were measured by graphite furnace atomic absorption. RESULTS: Severe, moderate and mild malnutrition were detected in 15%, 38% and 24% of human immunodeficiency virus infected individuals respectively. Compared with the healthy control group, serum level of zinc and selenium in the human immunodeficiency virus infected subjects were significantly lower (P = 0.01 and P = 0.02 respectively). CONCLUSION: Malnutrition found to be prevalent in Iranian human immunodeficiency virus infected individuals and low serum zinc and selenium levels are common in this population.
format Text
id pubmed-2613901
institution National Center for Biotechnology Information
language English
publishDate 2008
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-26139012009-01-06 Nutritional status and serum zinc and selenium levels in Iranian HIV infected individuals Khalili, H Soudbakhsh, A Hajiabdolbaghi, M Dashti-Khavidaki, S Poorzare, A Saeedi, AA Sharififar, R BMC Infect Dis Research Article BACKGROUND: Human immunodeficiency virus infected individuals are prone to malnutrition due to increased energy requirements, enteropathy and increased catabolism. Trace elements such as zinc and selenium have major role in maintaining a healthy immune system. This study was designed to evaluate the nutritional status of Iranian subjects who were newly diagnosed with human immunodeficiency virus infection and to compare serum level of zinc and selenium in these patients with those of the sex and aged match healthy subjects. METHODS: After an interview and physical examination, nutritional assessment was done based on clinical and anthropometric parameters. Body mass index (normal range 18.5–27 kg/m(2 )based on age) of less than 16, 16–16.9 and 17–18.4 kg/m(2 )were considered as severe, moderate and mild malnutrition respectively. Serum level of zinc and selenium were measured by graphite furnace atomic absorption. RESULTS: Severe, moderate and mild malnutrition were detected in 15%, 38% and 24% of human immunodeficiency virus infected individuals respectively. Compared with the healthy control group, serum level of zinc and selenium in the human immunodeficiency virus infected subjects were significantly lower (P = 0.01 and P = 0.02 respectively). CONCLUSION: Malnutrition found to be prevalent in Iranian human immunodeficiency virus infected individuals and low serum zinc and selenium levels are common in this population. BioMed Central 2008-12-09 /pmc/articles/PMC2613901/ /pubmed/19068104 http://dx.doi.org/10.1186/1471-2334-8-165 Text en Copyright © 2008 Khalili et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Khalili, H
Soudbakhsh, A
Hajiabdolbaghi, M
Dashti-Khavidaki, S
Poorzare, A
Saeedi, AA
Sharififar, R
Nutritional status and serum zinc and selenium levels in Iranian HIV infected individuals
title Nutritional status and serum zinc and selenium levels in Iranian HIV infected individuals
title_full Nutritional status and serum zinc and selenium levels in Iranian HIV infected individuals
title_fullStr Nutritional status and serum zinc and selenium levels in Iranian HIV infected individuals
title_full_unstemmed Nutritional status and serum zinc and selenium levels in Iranian HIV infected individuals
title_short Nutritional status and serum zinc and selenium levels in Iranian HIV infected individuals
title_sort nutritional status and serum zinc and selenium levels in iranian hiv infected individuals
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613901/
https://www.ncbi.nlm.nih.gov/pubmed/19068104
http://dx.doi.org/10.1186/1471-2334-8-165
work_keys_str_mv AT khalilih nutritionalstatusandserumzincandseleniumlevelsiniranianhivinfectedindividuals
AT soudbakhsha nutritionalstatusandserumzincandseleniumlevelsiniranianhivinfectedindividuals
AT hajiabdolbaghim nutritionalstatusandserumzincandseleniumlevelsiniranianhivinfectedindividuals
AT dashtikhavidakis nutritionalstatusandserumzincandseleniumlevelsiniranianhivinfectedindividuals
AT poorzarea nutritionalstatusandserumzincandseleniumlevelsiniranianhivinfectedindividuals
AT saeediaa nutritionalstatusandserumzincandseleniumlevelsiniranianhivinfectedindividuals
AT sharififarr nutritionalstatusandserumzincandseleniumlevelsiniranianhivinfectedindividuals