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Identification of a small optimal subset of CpG sites as bio-markers from high-throughput DNA methylation profiles

BACKGROUND: DNA methylation patterns have been shown to significantly correlate with different tissue types and disease states. High-throughput methylation arrays enable large-scale DNA methylation analysis to identify informative DNA methylation biomarkers. The identification of disease-specific me...

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Detalles Bibliográficos
Autores principales: Meng, Hailong, Murrelle, Edward L, Li, Guoya
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613930/
https://www.ncbi.nlm.nih.gov/pubmed/18954440
http://dx.doi.org/10.1186/1471-2105-9-457