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Taste, A New Incentive to Switch to (R)-Praziquantel in Schistosomiasis Treatment

BACKGROUND: Praziquantel (PZQ) is the drug compound of choice in the control and treatment of schistosomiasis. PZQ is administered as a racemate, i. e. 1∶1 mixture of enantiomers. The schistosomicidal activity arises from one PZQ-enantiomer, whereas the other enantiomer does not contribute to the ac...

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Detalles Bibliográficos
Autores principales: Meyer, Thorsten, Sekljic, Harald, Fuchs, Stefan, Bothe, Heiko, Schollmeyer, Dieter, Miculka, Christian
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2614124/
https://www.ncbi.nlm.nih.gov/pubmed/19159015
http://dx.doi.org/10.1371/journal.pntd.0000357