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Dissection of Functional Residues in Receptor Activity-Modifying Proteins Through Phylogenetic and Statistical Analyses
Type I and type-II functional divergences have been stated to highlight specific residues carrying out differential functions in evolutionary-divergent protein clusters from a single common ancestor. Briefly, type I analysis is based on residue constraints reflecting a gain of function just in one c...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Libertas Academica
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2614204/ https://www.ncbi.nlm.nih.gov/pubmed/19204815 |